Dose Response Analysis


Stratum 1
 
Exposure LevelCasesControlsTotalOdds of Exp.Odds Ratio
011311320.011
111041050.011.26
2451550.0810.27

Total6286292
Stratum 2
 
Exposure LevelCasesControlsTotalOdds of Exp.Odds Ratio
001881880'?'
161521580.04'?'
21583980.18'?'

Total21423444
Stratum 3
 
Exposure LevelCasesControlsTotalOdds of Exp.Odds Ratio
031611640.021
1121301420.094.95
22265870.3418.16

Total37356393
Stratum 4
 
Exposure LevelCasesControlsTotalOdds of Exp.Odds Ratio
0111691800.071
1211341550.162.41
239681070.578.81

Total71371442
Stratum 5
 
Exposure LevelCasesControlsTotalOdds of Exp.Odds Ratio
0231571800.151
142971390.432.96
23452860.654.46

Total99306405
 
Mantel-Haenszel Summary Odds Ratios and Crude OR for Each Exposure Level
ExposureMH Summary ORCrude OR
Level 0 vs. Level 0:11
Level 1 vs. Level 0:3.1582.819
Level 2 vs. Level 0:8.5637.58
 
If MH and crude ORs are equal, confounding by the stratifying variable
was not present and stratification is unnecessary.
 
Extended Mantel-Haenszel chi square for linear trend=128.83
p-value(1 degree of freedom)=<0.0000001
Includes continuity correction. Rosner,B. Fundamentals of Biostatistics, 5th ed.,Duxbury, 2000, p.606.
Results will therefore differ slightly from Statcalc and from Schlesselman,JJ,Case-Control Studies, Oxford, 1982,p.203.

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